A SECRET WEAPON FOR AHU HIRE

About 80% of TTP is induced by deficient exercise of ADAMTS13. ADAMTS13 deficiency could be constitutive, due to biallelic ADAMTS13 pathogenic variants; or acquired, as a result of an inhibitory antibody. Analysis of ADAMTS13 activity is executed employing assessments based on the potential with the protease to cleave regular VWF multimers in vitro